Innate Immunity and Asthma

Innate Immunity in Asthma.

It is appreciated that the marked increase in the prevalence of asthma over the past few decades reflects changes in environmental exposures and living conditions associated with modern lifestyles.1 Of particular interest is the documentation of a protective effect of exposures associated with traditional farming, the influence of which has waned with increased urbanization and the advent of me...

Asthma and innate immunity; current perspective.

Innate immunity and adjuvants

Innate immunity was for a long time considered to be non-specific because the major function of this system is to digest pathogens and present antigens to the cells involved in acquired immunity. However, recent studies have shown that innate immunity is not non-specific, but is instead sufficiently specific to discriminate self from pathogens through evolutionarily conserved receptors, designa...

Innate Immunity and Neuroinflammation

Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and comp...

Innate and acquired immunity

• The cells of the immune system are divided into lymphoid and myeloid lineages. The former include T lymphocytes and their subsets identified by CD markers, B lymphocytes and natural killer (NK) cells. The myeloid lineage includes the neutrophils, eosinophils and basophils as well as the monocyte/ macrophage series and platelets. • Innate immunity depends on physical, physiological and chemica...